Huvuduppslag - Personnamn
Titel och upphov Essential concepts in clinical research : randomised controlled trials and observational epidemiology
Varianttitel
Antal i kö: NU (US)
Utgivning, distribution, etc. Elsevier, Edinburgh : 2019.
National Library of Medicine (NLM) klassifikationskod
DDC klassifikationskod (Dewey Decimal Classification)
Upplaga
Fysisk beskrivning 1 online resource (x, 256 pages) : color illustrations
Anmärkning: Allmän Revised edition of: The Lancet handbook of essential concepts in clinical research / by Kenneth F. Schulz, David A. Grimes ; foreword by Richard Horton. 2006.
Anmärkning: Bibliografi etc. Includes bibliographical references
Anmärkning: Innehåll Introduction. An overview of clinical research: the lay of the land -- Observational studies. Descriptive studies: what they can and cannot do -- Bias and causal associations in observational research -- Cohort studies: marching towards outcomes -- Case-control studies: research in reverse -- Finding controls for case-control studies: compared to what? -- Limitations of observational epidemiology -- Screening tests. Uses and abuses of screening tests -- Refining clinical diagnosis with likelihood ratios -- Randomized controlled trials. Boosting participant recruitment in trials -- Sample size calculations in randomized trials: mandatory and mystical -- Generation of allocation sequences in randomized trials: chance not choice -- Generation of allocation sequences in non-double-blinded randomized trials: guarding against guessing -- Allocation concealment in randomized trials: defending against deciphering -- Exclusions and losses in randomized trials: sample size slippages -- Blinding in randomized trials: hiding who got what -- Implementing treatment blinding in randomized trials -- Surrogate endpoints and composite outcomes: shortcuts to unknown destinations -- Multiplicity in randomized trials I: endpoints and treatments -- Multiplicity in randomized trials II: subgroup and interim analyses -- Conducting randomized trials as part of a prospective meta-analysis -- Publishing. Reporting studies in medical journals: CONSORT and other guidelines.
Anmärkning: Innehållsbeskrivning, sammanfattning "This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials"--Publisher's description.
Ämnesordsbiuppslag - Term
Indexterm - Genre/Form Electronic books. Fulltext. Internet Resources.
Biuppslag - Personnamn
Länkfält - Annat medium Print version: Schulz, Kenneth F. Essential concepts in clinical research : randomised controlled trials and observational epidemiology. Second edition. Edinburgh : Elsevier, 2019 275 pages ISBN 9780702073946
ISBN
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*100 $aSchulz, Kenneth F.,$eauthor.
*24010$aLancet handbook of essential concepts in clinical research
*24510$aEssential concepts in clinical research :$brandomised controlled trials and observational epidemiology /$cKenneth Schulz, David A. Grimes ; foreword by Richard Horton.
*246 3$aClinical research
*250 $aSecond edition.
*264 1$aEdinburgh :$bElsevier,$c2019.
*300 $a1 online resource (x, 256 pages) :$bcolor illustrations
*336 $atext$btxt$2rdacontent
*337 $acomputer$bc$2rdamedia
*338 $aonline resource$bcr$2rdacarrier
*500 $aRevised edition of: The Lancet handbook of essential concepts in clinical research / by Kenneth F. Schulz, David A. Grimes ; foreword by Richard Horton. 2006.
*504 $aIncludes bibliographical references
*505 0$aIntroduction. An overview of clinical research: the lay of the land -- Observational studies. Descriptive studies: what they can and cannot do -- Bias and causal associations in observational research -- Cohort studies: marching towards outcomes -- Case-control studies: research in reverse -- Finding controls for case-control studies: compared to what? -- Limitations of observational epidemiology -- Screening tests. Uses and abuses of screening tests -- Refining clinical diagnosis with likelihood ratios -- Randomized controlled trials. Boosting participant recruitment in trials -- Sample size calculations in randomized trials: mandatory and mystical -- Generation of allocation sequences in randomized trials: chance not choice -- Generation of allocation sequences in non-double-blinded randomized trials: guarding against guessing -- Allocation concealment in randomized trials: defending against deciphering -- Exclusions and losses in randomized trials: sample size slippages -- Blinding in randomized trials: hiding who got what -- Implementing treatment blinding in randomized trials -- Surrogate endpoints and composite outcomes: shortcuts to unknown destinations -- Multiplicity in randomized trials I: endpoints and treatments -- Multiplicity in randomized trials II: subgroup and interim analyses -- Conducting randomized trials as part of a prospective meta-analysis -- Publishing. Reporting studies in medical journals: CONSORT and other guidelines.
*520 $a"This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials"--Publisher's description.
*588 $aDescription based on online resource; title from resource home page (ClinicalKey, viewed March 7, 2019).
*650 0$aClinical medicine$xResearch.
*650 0$aMedicine$xResearch.
*650 0$aClinical trials.
*65012$aRandomized Controlled Trials as Topic.
*65022$aEpidemiologic Studies.
*650 7$aClinical medicine$xResearch.$2fast$0(OCoLC)fst00864379
*650 7$aClinical trials.$2fast$0(OCoLC)fst00864429
*650 7$aMedicine$xResearch.$2fast$0(OCoLC)fst01015059
*655 0$aElectronic books.
*655 4$aFulltext.
*655 4$aInternet Resources.
*700 $aGrimes, David A.,$eauthor.
*700 $aHorton, Richard C.,$ewriter of foreword.
*700 $iPreceded by:$aSchulz, Kenneth F.$tLancet handbook of essential concepts in clinical research.$f2006.
*77608$iPrint version:$aSchulz, Kenneth F.$tEssential concepts in clinical research : randomised controlled trials and observational epidemiology.$bSecond edition.$dEdinburgh : Elsevier, 2019$h275 pages$z9780702073946$wIMP(OCoLC)(OCoLC)1019998720
*85640$uhttp://proxybibl.vgregion.se/login?url=https://www.clinicalkey.com/dura/browse/bookChapter/3-s2.0-C20160034812$zTillgänglig via e-biblioteket Västra Götalandsregionen
*994 $a92$bSENUS
^
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